Entity Details

Primary name CCL5_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP30882
EntryNameCCL5_MOUSE
FullNameC-C motif chemokine 5
TaxID10090
Evidenceevidence at protein level
Length91
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesCcl5

GO terms

Show/Hide Table
GOName
GO:0000165 MAPK cascade
GO:0002230 positive regulation of defense response to virus by host
GO:0002548 monocyte chemotaxis
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0004672 protein kinase activity
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0006816 calcium ion transport
GO:0006874 cellular calcium ion homeostasis
GO:0006887 exocytosis
GO:0006954 inflammatory response
GO:0007159 leukocyte cell-cell adhesion
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0008009 chemokine activity
GO:0008201 heparin binding
GO:0009636 response to toxic substance
GO:0010628 positive regulation of gene expression
GO:0010759 positive regulation of macrophage chemotaxis
GO:0010820 positive regulation of T cell chemotaxis
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0014911 positive regulation of smooth muscle cell migration
GO:0016004 phospholipase activator activity
GO:0030298 receptor signaling protein tyrosine kinase activator activity
GO:0030335 positive regulation of cell migration
GO:0030593 neutrophil chemotaxis
GO:0031269 pseudopodium assembly
GO:0031328 positive regulation of cellular biosynthetic process
GO:0031584 activation of phospholipase D activity
GO:0031622 positive regulation of fever generation
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0031726 CCR1 chemokine receptor binding
GO:0031730 CCR5 chemokine receptor binding
GO:0033634 positive regulation of cell-cell adhesion mediated by integrin
GO:0034097 response to cytokine
GO:0034112 positive regulation of homotypic cell-cell adhesion
GO:0034341 response to interferon-gamma
GO:0034612 response to tumor necrosis factor
GO:0035688 T-helper 1 cell diapedesis
GO:0042056 chemoattractant activity
GO:0042102 positive regulation of T cell proliferation
GO:0042119 neutrophil activation
GO:0042327 positive regulation of phosphorylation
GO:0042379 chemokine receptor binding
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043491 protein kinase B signaling
GO:0043547 positive regulation of GTPase activity
GO:0043621 protein self-association
GO:0043922 negative regulation by host of viral transcription
GO:0045071 negative regulation of viral genome replication
GO:0045666 positive regulation of neuron differentiation
GO:0045672 positive regulation of osteoclast differentiation
GO:0045744 negative regulation of G protein-coupled receptor signaling pathway
GO:0045766 positive regulation of angiogenesis
GO:0045785 positive regulation of cell adhesion
GO:0046817 chemokine receptor antagonist activity
GO:0048020 CCR chemokine receptor binding
GO:0048245 eosinophil chemotaxis
GO:0048247 lymphocyte chemotaxis
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0050679 positive regulation of epithelial cell proliferation
GO:0050796 regulation of insulin secretion
GO:0050863 regulation of T cell activation
GO:0051928 positive regulation of calcium ion transport
GO:0060548 negative regulation of cell death
GO:0060754 positive regulation of mast cell chemotaxis
GO:0070098 chemokine-mediated signaling pathway
GO:0070233 negative regulation of T cell apoptotic process
GO:0070234 positive regulation of T cell apoptotic process
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071407 cellular response to organic cyclic compound
GO:0090026 positive regulation of monocyte chemotaxis
GO:1901214 regulation of neuron death
GO:1901215 negative regulation of neuron death
GO:2000110 negative regulation of macrophage apoptotic process
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production
GO:2000406 positive regulation of T cell migration
GO:2000503 positive regulation of natural killer cell chemotaxis

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR000827 CC chemokine, conserved siteSiteConserved site
IPR001811 Chemokine interleukin-8-like domainDomainDomain
IPR036048 Chemokine interleukin-8-like superfamilyFamilyHomologous superfamily
IPR039809 Chemokine beta/gamma/deltaFamilyFamily

Diseases

Show/Hide Table

Interactions

3 interactions