Entity Details

Primary name SYNE1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NF91
EntryNameSYNE1_HUMAN
FullNameNesprin-1
TaxID9606
Evidenceevidence at protein level
Length8797
SequenceStatuscomplete
DateCreated2003-04-11
DateModified2021-06-02

Ontological Relatives

GenesSYNE1

GO terms

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GOName
GO:0000932 P-body
GO:0003723 RNA binding
GO:0003779 actin binding
GO:0005521 lamin binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005640 nuclear outer membrane
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005856 cytoskeleton
GO:0006997 nucleus organization
GO:0007030 Golgi organization
GO:0007283 spermatogenesis
GO:0016021 integral component of membrane
GO:0019899 enzyme binding
GO:0030017 sarcomere
GO:0031965 nuclear membrane
GO:0034993 meiotic nuclear membrane microtubule tethering complex
GO:0042692 muscle cell differentiation
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0045211 postsynaptic membrane
GO:0051015 actin filament binding
GO:0090292 nuclear matrix anchoring at nuclear membrane
GO:0140444 cytoskeleton-nuclear membrane anchor activity

Subcellular Location

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Subcellular Location
Cytoplasm
Golgi apparatus
Nucleus
Nucleus envelope
Nucleus outer membrane

Domains

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DomainNameCategoryType
IPR001589 Actinin-type actin-binding domain, conserved siteSiteConserved site
IPR001715 Calponin homology domainDomainDomain
IPR002017 Spectrin repeatRepeatRepeat
IPR012315 KASH domainDomainDomain
IPR018159 Spectrin/alpha-actininRepeatRepeat
IPR036872 CH domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SYNE1_HUMANEMD_MOUSEIntAct17462627 details