Entity Details

Primary name SUH_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP31266
EntryNameSUH_MOUSE
FullNameRecombining binding protein suppressor of hairless
TaxID10090
Evidenceevidence at protein level
Length526
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesRbpj

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0001756 somitogenesis
GO:0001837 epithelial to mesenchymal transition
GO:0001947 heart looping
GO:0001974 blood vessel remodeling
GO:0002193 MAML1-RBP-Jkappa- ICN1 complex
GO:0002437 inflammatory response to antigenic stimulus
GO:0003139 secondary heart field specification
GO:0003151 outflow tract morphogenesis
GO:0003157 endocardium development
GO:0003160 endocardium morphogenesis
GO:0003176 aortic valve development
GO:0003177 pulmonary valve development
GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003214 cardiac left ventricle morphogenesis
GO:0003222 ventricular trabecula myocardium morphogenesis
GO:0003256 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006959 humoral immune response
GO:0007219 Notch signaling pathway
GO:0007221 positive regulation of transcription of Notch receptor target
GO:0007507 heart development
GO:0008134 transcription factor binding
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0009912 auditory receptor cell fate commitment
GO:0009957 epidermal cell fate specification
GO:0010468 regulation of gene expression
GO:0010628 positive regulation of gene expression
GO:0010977 negative regulation of neuron projection development
GO:0014912 negative regulation of smooth muscle cell migration
GO:0017053 transcription repressor complex
GO:0021983 pituitary gland development
GO:0030097 hemopoiesis
GO:0030182 neuron differentiation
GO:0030183 B cell differentiation
GO:0030216 keratinocyte differentiation
GO:0030279 negative regulation of ossification
GO:0030513 positive regulation of BMP signaling pathway
GO:0032991 protein-containing complex
GO:0032993 protein-DNA complex
GO:0034392 negative regulation of smooth muscle cell apoptotic process
GO:0035019 somatic stem cell population maintenance
GO:0035481 positive regulation of Notch signaling pathway involved in heart induction
GO:0035912 dorsal aorta morphogenesis
GO:0036302 atrioventricular canal development
GO:0042127 regulation of cell population proliferation
GO:0042742 defense response to bacterium
GO:0043011 myeloid dendritic cell differentiation
GO:0043565 sequence-specific DNA binding
GO:0044877 protein-containing complex binding
GO:0045165 cell fate commitment
GO:0045596 negative regulation of cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0047485 protein N-terminus binding
GO:0048505 regulation of timing of cell differentiation
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0048733 sebaceous gland development
GO:0048820 hair follicle maturation
GO:0048844 artery morphogenesis
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060412 ventricular septum morphogenesis
GO:0060486 club cell differentiation
GO:0060716 labyrinthine layer blood vessel development
GO:0060844 arterial endothelial cell fate commitment
GO:0060853 Notch signaling pathway involved in arterial endothelial cell fate commitment
GO:0061344 regulation of cell adhesion involved in heart morphogenesis
GO:0061371 determination of heart left/right asymmetry
GO:0061419 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0072554 blood vessel lumenization
GO:0097101 blood vessel endothelial cell fate specification
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1901186 positive regulation of ERBB signaling pathway
GO:1901189 positive regulation of ephrin receptor signaling pathway
GO:1901297 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR015350 Beta-trefoil DNA-binding domainDomainDomain
IPR015351 RBP-J/Cbf11/Cbf12, DNA bindingDomainDomain
IPR036358 Beta-trefoil domain superfamilyFamilyHomologous superfamily
IPR037095 RBP-J/Cbf11, DNA binding domain superfamilyFamilyHomologous superfamily
IPR038007 RBP-Jkappa, IPT domainDomainDomain
IPR040159 Suppressor of hairless-likeFamilyFamily

Diseases

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