Entity Details

Primary name SC6A1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP31648
EntryNameSC6A1_MOUSE
FullNameSodium- and chloride-dependent GABA transporter 1
TaxID10090
Evidenceevidence at protein level
Length599
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesSlc6a1

GO terms

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GOName
GO:0005332 gamma-aminobutyric acid:sodium symporter activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007612 learning
GO:0007613 memory
GO:0008306 associative learning
GO:0009636 response to toxic substance
GO:0009744 response to sucrose
GO:0009986 cell surface
GO:0010033 response to organic substance
GO:0010035 response to inorganic substance
GO:0010288 response to lead ion
GO:0014054 positive regulation of gamma-aminobutyric acid secretion
GO:0014074 response to purine-containing compound
GO:0015185 gamma-aminobutyric acid transmembrane transporter activity
GO:0015378 sodium:chloride symporter activity
GO:0030424 axon
GO:0032229 negative regulation of synaptic transmission, GABAergic
GO:0032355 response to estradiol
GO:0035725 sodium ion transmembrane transport
GO:0042220 response to cocaine
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0046872 metal ion binding
GO:0050808 synapse organization
GO:0051592 response to calcium ion
GO:0051939 gamma-aminobutyric acid import
GO:0098658 inorganic anion import across plasma membrane
GO:0098719 sodium ion import across plasma membrane
GO:0098810 neurotransmitter reuptake
GO:0098982 GABA-ergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099056 integral component of presynaptic membrane
GO:1902476 chloride transmembrane transport

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Membrane

Domains

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DomainNameCategoryType
IPR000175 Sodium:neurotransmitter symporterFamilyFamily
IPR002980 Sodium:neurotransmitter symporter, GABA, GAT-1FamilyFamily
IPR037272 Sodium:neurotransmitter symporter superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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