Entity Details

Primary name AREG_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP31955
EntryNameAREG_MOUSE
FullNameAmphiregulin
TaxID10090
Evidenceevidence at transcript level
Length248
SequenceStatuscomplete
DateCreated1993-07-01
DateModified2021-06-02

Ontological Relatives

GenesAreg

GO terms

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GOName
GO:0005125 cytokine activity
GO:0005154 epidermal growth factor receptor binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0009986 cell surface
GO:0014009 glial cell proliferation
GO:0016021 integral component of membrane
GO:0031175 neuron projection development
GO:0032355 response to estradiol
GO:0042327 positive regulation of phosphorylation
GO:0042542 response to hydrogen peroxide
GO:0043434 response to peptide hormone
GO:0045668 negative regulation of osteoblast differentiation
GO:0045741 positive regulation of epidermal growth factor-activated receptor activity
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051384 response to glucocorticoid
GO:0051591 response to cAMP
GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
GO:0060744 mammary gland branching involved in thelarche
GO:0060749 mammary gland alveolus development
GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000742 EGF-like domainDomainDomain
IPR015497 Epidermal growth factor receptor ligandFamilyFamily

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink