Entity Details

Primary name PAX4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP32115
EntryNamePAX4_MOUSE
FullNamePaired box protein Pax-4
TaxID10090
Evidenceevidence at protein level
Length349
SequenceStatuscomplete
DateCreated1993-10-01
DateModified2021-06-02

Ontological Relatives

GenesPax4

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007623 circadian rhythm
GO:0009887 animal organ morphogenesis
GO:0030154 cell differentiation
GO:0031016 pancreas development
GO:0042493 response to drug
GO:0043066 negative regulation of apoptotic process
GO:0045595 regulation of cell differentiation
GO:0045597 positive regulation of cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048856 anatomical structure development
GO:0051591 response to cAMP
GO:0060041 retina development in camera-type eye
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR001523 Paired domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR033559 Paired box protein Pax-4FamilyFamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR043182 Paired DNA-binding domainDomainDomain
IPR043565 PAX familyFamilyFamily

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink