Entity Details

Primary name COP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NHY2
EntryNameCOP1_HUMAN
FullNameE3 ubiquitin-protein ligase COP1
TaxID9606
Evidenceevidence at protein level
Length731
SequenceStatuscomplete
DateCreated2004-11-23
DateModified2021-06-02

Ontological Relatives

GenesCOP1

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0010212 response to ionizing radiation
GO:0016607 nuclear speck
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043687 post-translational protein modification
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus speckle

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily
IPR042755 E3 ubiquitin-protein ligase COP1FamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
COP1_HUMANTRIB1_MOUSEBioGRID23884858 details