Entity Details

Primary name RIN3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TB24
EntryNameRIN3_HUMAN
FullNameRas and Rab interactor 3
TaxID9606
Evidenceevidence at protein level
Length985
SequenceStatuscomplete
DateCreated2003-02-01
DateModified2021-06-02

Ontological Relatives

GenesRIN3

GO terms

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GOName
GO:0002091 negative regulation of receptor internalization
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005829 cytosol
GO:0006897 endocytosis
GO:0007165 signal transduction
GO:0030139 endocytic vesicle
GO:0030424 axon
GO:0030425 dendrite
GO:0031267 small GTPase binding
GO:0031410 cytoplasmic vesicle
GO:0031982 vesicle
GO:0043025 neuronal cell body
GO:0043547 positive regulation of GTPase activity
GO:0060755 negative regulation of mast cell chemotaxis
GO:0097494 regulation of vesicle size

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle
Early endosome

Domains

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DomainNameCategoryType
IPR000159 Ras-associating (RA) domainDomainDomain
IPR000980 SH2 domainDomainDomain
IPR003123 VPS9 domainDomainDomain
IPR035869 Ras and Rab interactor 3, SH2 domainDomainDomain
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily
IPR037191 VPS9 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
RIN3_HUMANBIN1_MOUSEIntAct32552912 details
RIN3_HUMANCD2AP_MOUSEIntAct32552912 details