Entity Details

Primary name PI42C_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TBX8
EntryNamePI42C_HUMAN
FullNamePhosphatidylinositol 5-phosphate 4-kinase type-2 gamma
TaxID9606
Evidenceevidence at protein level
Length421
SequenceStatuscomplete
DateCreated2007-05-01
DateModified2021-06-02

Ontological Relatives

GenesPIP4K2C

GO terms

Show/Hide Table
GOName
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005776 autophagosome
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006661 phosphatidylinositol biosynthetic process
GO:0010506 regulation of autophagy
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling
GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity
GO:0042802 identical protein binding
GO:0043229 intracellular organelle
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0070062 extracellular exosome
GO:0090217 negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:1902635 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process
GO:2000786 positive regulation of autophagosome assembly

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Endoplasmic reticulum

Domains

Show/Hide Table
DomainNameCategoryType
IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, coreDomainDomain
IPR023610 Phosphatidylinositol-4-phosphate 5-kinaseFamilyFamily
IPR027484 Phosphatidylinositol-4-phosphate 5-kinase, N-terminalFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink