Entity Details

Primary name PARD3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TEW0
EntryNamePARD3_HUMAN
FullNamePartitioning defective 3 homolog
TaxID9606
Evidenceevidence at protein level
Length1356
SequenceStatuscomplete
DateCreated2003-05-16
DateModified2021-06-02

Ontological Relatives

GenesPARD3

GO terms

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GOName
GO:0000226 microtubule cytoskeleton organization
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005923 bicellular tight junction
GO:0005938 cell cortex
GO:0006612 protein targeting to membrane
GO:0007049 cell cycle
GO:0007155 cell adhesion
GO:0007163 establishment or maintenance of cell polarity
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway
GO:0007409 axonogenesis
GO:0008104 protein localization
GO:0008356 asymmetric cell division
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0012505 endomembrane system
GO:0016324 apical plasma membrane
GO:0019903 protein phosphatase binding
GO:0022011 myelination in peripheral nervous system
GO:0030010 establishment of cell polarity
GO:0030054 cell junction
GO:0031643 positive regulation of myelination
GO:0032266 phosphatidylinositol-3-phosphate binding
GO:0032991 protein-containing complex
GO:0033269 internode region of axon
GO:0035091 phosphatidylinositol binding
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043296 apical junction complex
GO:0044295 axonal growth cone
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
GO:0051660 establishment of centrosome localization
GO:0060341 regulation of cellular localization
GO:0065003 protein-containing complex assembly
GO:0070830 bicellular tight junction assembly
GO:0090162 establishment of epithelial cell polarity

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cytoplasm
Endomembrane system

Domains

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DomainNameCategoryType
IPR001478 PDZ domainDomainDomain
IPR021922 Par3/HAL, N-terminalDomainDomain
IPR036034 PDZ superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions