Entity Details

Primary name AP2A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP34056
EntryNameAP2A_MOUSE
FullNameTranscription factor AP-2-alpha
TaxID10090
Evidenceevidence at protein level
Length437
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesTfap2a

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001822 kidney development
GO:0001843 neural tube closure
GO:0002089 lens morphogenesis in camera-type eye
GO:0003151 outflow tract morphogenesis
GO:0003334 keratinocyte development
GO:0003404 optic vesicle morphogenesis
GO:0003409 optic cup structural organization
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005829 cytosol
GO:0005905 clathrin-coated pit
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007399 nervous system development
GO:0007423 sensory organ development
GO:0007605 sensory perception of sound
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0009880 embryonic pattern specification
GO:0010172 embryonic body morphogenesis
GO:0010628 positive regulation of gene expression
GO:0010944 negative regulation of transcription by competitive promoter binding
GO:0014032 neural crest cell development
GO:0021506 anterior neuropore closure
GO:0021559 trigeminal nerve development
GO:0021623 oculomotor nerve formation
GO:0021884 forebrain neuron development
GO:0030335 positive regulation of cell migration
GO:0030501 positive regulation of bone mineralization
GO:0032496 response to lipopolysaccharide
GO:0035115 embryonic forelimb morphogenesis
GO:0035136 forelimb morphogenesis
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0042127 regulation of cell population proliferation
GO:0042472 inner ear morphogenesis
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0043588 skin development
GO:0045595 regulation of cell differentiation
GO:0045664 regulation of neuron differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048485 sympathetic nervous system development
GO:0048596 embryonic camera-type eye morphogenesis
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0048705 skeletal system morphogenesis
GO:0048730 epidermis morphogenesis
GO:0048856 anatomical structure development
GO:0060021 roof of mouth development
GO:0060235 lens induction in camera-type eye
GO:0060325 face morphogenesis
GO:0060349 bone morphogenesis
GO:0061029 eyelid development in camera-type eye
GO:0061303 cornea development in camera-type eye
GO:0070172 positive regulation of tooth mineralization
GO:0071281 cellular response to iron ion
GO:0071711 basement membrane organization
GO:0072210 metanephric nephron development
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000378 negative regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR004979 Transcription factor AP-2FamilyFamily
IPR008121 Transcription factor AP-2 alpha, N-terminalDomainDomain
IPR013854 Transcription factor AP-2, C-terminalDomainDomain

Diseases

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Interactions

4 interactions