Entity Details

Primary name HDAC7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WUI4
EntryNameHDAC7_HUMAN
FullNameHistone deacetylase 7
TaxID9606
Evidenceevidence at protein level
Length952
SequenceStatuscomplete
DateCreated2003-05-16
DateModified2021-06-02

Ontological Relatives

GenesHDAC7

GO terms

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GOName
GO:0000118 histone deacetylase complex
GO:0005080 protein kinase C binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006476 protein deacetylation
GO:0019901 protein kinase binding
GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032703 negative regulation of interleukin-2 production
GO:0033558 protein deacetylase activity
GO:0045668 negative regulation of osteoblast differentiation
GO:0046872 metal ion binding
GO:0071889 14-3-3 protein binding
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
GO:1901223 negative regulation of NIK/NF-kappaB signaling

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000286 Histone deacetylase familyFamilyFamily
IPR017320 Histone deacetylase class II, eukaryoticFamilyFamily
IPR023696 Ureohydrolase domain superfamilyFamilyHomologous superfamily
IPR023801 Histone deacetylase domainDomainDomain
IPR037138 Histone deacetylase domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04297 Trichostatin ADrugbanksmall molecule
DB05015 BelinostatDrugbanksmall molecule
DB06603 PanobinostatDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
HDAC7_HUMANPPARD_MOUSEBioGRID12970571 details
HDAC7_HUMANMEF2C_MOUSEDIP23565059 details