Entity Details

Primary name 5HT2C_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP34968
EntryName5HT2C_MOUSE
FullName5-hydroxytryptamine receptor 2C
TaxID10090
Evidenceevidence at transcript level
Length459
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesHtr2c

GO terms

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GOName
GO:0001587 Gq/11-coupled serotonin receptor activity
GO:0001662 behavioral fear response
GO:0004993 G protein-coupled serotonin receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006874 cellular calcium ion homeostasis
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007208 phospholipase C-activating serotonin receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007626 locomotory behavior
GO:0007631 feeding behavior
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010513 positive regulation of phosphatidylinositol biosynthetic process
GO:0014054 positive regulation of gamma-aminobutyric acid secretion
GO:0014057 positive regulation of acetylcholine secretion, neurotransmission
GO:0019934 cGMP-mediated signaling
GO:0030425 dendrite
GO:0030594 neurotransmitter receptor activity
GO:0031583 phospholipase D-activating G protein-coupled receptor signaling pathway
GO:0031644 regulation of nervous system process
GO:0032098 regulation of appetite
GO:0035095 behavioral response to nicotine
GO:0040013 negative regulation of locomotion
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0043397 regulation of corticotropin-releasing hormone secretion
GO:0045202 synapse
GO:0045600 positive regulation of fat cell differentiation
GO:0045907 positive regulation of vasoconstriction
GO:0045963 negative regulation of dopamine metabolic process
GO:0048016 inositol phosphate-mediated signaling
GO:0051209 release of sequestered calcium ion into cytosol
GO:0051378 serotonin binding
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0051930 regulation of sensory perception of pain
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
GO:0098664 G protein-coupled serotonin receptor signaling pathway
GO:0098666 G protein-coupled serotonin receptor complex

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000377 5-Hydroxytryptamine 2C receptorFamilyFamily
IPR002231 5-hydroxytryptamine receptor familyFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

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