Entity Details

Primary name ADRB1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP34971
EntryNameADRB1_MOUSE
FullNameBeta-1 adrenergic receptor
TaxID10090
Evidenceevidence at protein level
Length466
SequenceStatuscomplete
DateCreated1994-02-01
DateModified2021-06-02

Ontological Relatives

GenesAdrb1

GO terms

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GOName
GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine
GO:0001997 positive regulation of the force of heart contraction by epinephrine-norepinephrine
GO:0002024 diet induced thermogenesis
GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
GO:0003061 positive regulation of the force of heart contraction by norepinephrine
GO:0003084 positive regulation of systemic arterial blood pressure
GO:0004930 G protein-coupled receptor activity
GO:0004940 beta1-adrenergic receptor activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005980 glycogen catabolic process
GO:0006915 apoptotic process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007266 Rho protein signal transduction
GO:0007613 memory
GO:0009409 response to cold
GO:0010460 positive regulation of heart rate
GO:0016020 membrane
GO:0019233 sensory perception of pain
GO:0030165 PDZ domain binding
GO:0031649 heat generation
GO:0031694 alpha-2A adrenergic receptor binding
GO:0033365 protein localization to organelle
GO:0035811 negative regulation of urine volume
GO:0040015 negative regulation of multicellular organism growth
GO:0042060 wound healing
GO:0042596 fear response
GO:0043065 positive regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043547 positive regulation of GTPase activity
GO:0045187 regulation of circadian sleep/wake cycle, sleep
GO:0045762 positive regulation of adenylate cyclase activity
GO:0045986 negative regulation of smooth muscle contraction
GO:0046878 positive regulation of saliva secretion
GO:0046982 protein heterodimerization activity
GO:0050873 brown fat cell differentiation
GO:0051924 regulation of calcium ion transport
GO:0055088 lipid homeostasis
GO:0060080 inhibitory postsynaptic potential
GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
GO:0086004 regulation of cardiac muscle cell contraction
GO:0098685 Schaffer collateral - CA1 synapse
GO:0098794 postsynapse
GO:0099579 G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
GO:0106071 positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1900135 positive regulation of renin secretion into blood stream
GO:1900273 positive regulation of long-term synaptic potentiation
GO:1905665 positive regulation of calcium ion import across plasma membrane
GO:2001259 positive regulation of cation channel activity

Subcellular Location

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Subcellular Location
Cell membrane
Early endosome

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000507 Beta 1 adrenoceptorFamilyFamily
IPR002233 Adrenoceptor familyFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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