Entity Details

Primary name CXCR2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP35343
EntryNameCXCR2_MOUSE
FullNameC-X-C chemokine receptor type 2
TaxID10090
Evidenceevidence at transcript level
Length359
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesCxcr2

GO terms

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GOName
GO:0002438 acute inflammatory response to antigenic stimulus
GO:0002690 positive regulation of leukocyte chemotaxis
GO:0004918 interleukin-8 receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0004950 chemokine receptor activity
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0006935 chemotaxis
GO:0006955 immune response
GO:0006968 cellular defense response
GO:0007166 cell surface receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008284 positive regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010666 positive regulation of cardiac muscle cell apoptotic process
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016493 C-C chemokine receptor activity
GO:0016494 C-X-C chemokine receptor activity
GO:0019722 calcium-mediated signaling
GO:0019957 C-C chemokine binding
GO:0019959 interleukin-8 binding
GO:0030593 neutrophil chemotaxis
GO:0030901 midbrain development
GO:0031623 receptor internalization
GO:0033030 negative regulation of neutrophil apoptotic process
GO:0038112 interleukin-8-mediated signaling pathway
GO:0042119 neutrophil activation
GO:0042629 mast cell granule
GO:0043066 negative regulation of apoptotic process
GO:0043117 positive regulation of vascular permeability
GO:0045766 positive regulation of angiogenesis
GO:0060326 cell chemotaxis
GO:0072173 metanephric tubule morphogenesis
GO:0072686 mitotic spindle
GO:0090023 positive regulation of neutrophil chemotaxis

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000057 CXC chemokine receptor 2FamilyFamily
IPR000174 CXC chemokine receptor 1/2FamilyFamily
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

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