Entity Details

Primary name CRFR1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP35347
EntryNameCRFR1_MOUSE
FullNameCorticotropin-releasing factor receptor 1
TaxID10090
Evidenceevidence at protein level
Length415
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesCrhr1

GO terms

Show/Hide Table
GOName
GO:0001666 response to hypoxia
GO:0001965 G-protein alpha-subunit binding
GO:0004930 G protein-coupled receptor activity
GO:0005771 multivesicular body
GO:0005802 trans-Golgi network
GO:0005886 plasma membrane
GO:0007166 cell surface receptor signaling pathway
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007218 neuropeptide signaling pathway
GO:0007613 memory
GO:0007631 feeding behavior
GO:0008528 G protein-coupled peptide receptor activity
GO:0008542 visual learning
GO:0010578 regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway
GO:0015056 corticotrophin-releasing factor receptor activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0017046 peptide hormone binding
GO:0021854 hypothalamus development
GO:0030325 adrenal gland development
GO:0030425 dendrite
GO:0030855 epithelial cell differentiation
GO:0031226 intrinsic component of plasma membrane
GO:0031982 vesicle
GO:0032811 negative regulation of epinephrine secretion
GO:0035641 locomotory exploration behavior
GO:0035902 response to immobilization stress
GO:0042277 peptide binding
GO:0042596 fear response
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043306 positive regulation of mast cell degranulation
GO:0043404 corticotropin-releasing hormone receptor activity
GO:0043950 positive regulation of cAMP-mediated signaling
GO:0044877 protein-containing complex binding
GO:0045177 apical part of cell
GO:0048148 behavioral response to cocaine
GO:0048149 behavioral response to ethanol
GO:0048167 regulation of synaptic plasticity
GO:0048266 behavioral response to pain
GO:0051424 corticotropin-releasing hormone binding
GO:0051458 corticotropin secretion
GO:0051602 response to electrical stimulus
GO:0051867 general adaptation syndrome, behavioral process
GO:0060291 long-term synaptic potentiation
GO:0071376 cellular response to corticotropin-releasing hormone stimulus
GO:1901215 negative regulation of neuron death
GO:1901386 negative regulation of voltage-gated calcium channel activity
GO:2000252 negative regulation of feeding behavior
GO:2000852 regulation of corticosterone secretion

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Endosome

Domains

Show/Hide Table
DomainNameCategoryType
IPR000832 GPCR, family 2, secretin-likeFamilyFamily
IPR001879 GPCR, family 2, extracellular hormone receptor domainDomainDomain
IPR003051 GPCR, family 2, corticotropin releasing factor receptorFamilyFamily
IPR003052 GPCR, family 2, corticotropin releasing factor receptor, type 1FamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR017983 GPCR, family 2, secretin-like, conserved siteSiteConserved site
IPR036445 GPCR family 2, extracellular hormone receptor domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

3 interactions