Entity Details

Primary name P55G_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92569
EntryNameP55G_HUMAN
FullNamePhosphatidylinositol 3-kinase regulatory subunit gamma
TaxID9606
Evidenceevidence at protein level
Length461
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesPIK3R3

GO terms

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GOName
GO:0001784 phosphotyrosine residue binding
GO:0001934 positive regulation of protein phosphorylation
GO:0002042 cell migration involved in sprouting angiogenesis
GO:0005829 cytosol
GO:0005942 phosphatidylinositol 3-kinase complex
GO:0006661 phosphatidylinositol biosynthetic process
GO:0008286 insulin receptor signaling pathway
GO:0010628 positive regulation of gene expression
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0030335 positive regulation of cell migration
GO:0043491 protein kinase B signaling
GO:0043551 regulation of phosphatidylinositol 3-kinase activity
GO:0046854 phosphatidylinositol phosphate biosynthetic process
GO:0046935 1-phosphatidylinositol-3-kinase regulator activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR032498 PI3K regulatory subunit p85-related , inter-SH2 domainDomainDomain
IPR035020 PI3K p85 subunit, C-terminal SH2 domainDomainDomain
IPR035022 PI3K p85 subunit, N-terminal SH2 domainDomainDomain
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01064 IsoprenalineDrugbanksmall molecule
DB05210 SF1126Drugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
P55G_HUMANIRS1_MOUSEIntAct25814554 details