Entity Details

Primary name HS105_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92598
EntryNameHS105_HUMAN
FullNameHeat shock protein 105 kDa
TaxID9606
Evidenceevidence at protein level
Length858
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesHSPH1

GO terms

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GOName
GO:0000774 adenyl-nucleotide exchange factor activity
GO:0005524 ATP binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005874 microtubule
GO:0006898 receptor-mediated endocytosis
GO:0006986 response to unfolded protein
GO:0016887 ATP hydrolysis activity
GO:0032991 protein-containing complex
GO:0043014 alpha-tubulin binding
GO:0045345 positive regulation of MHC class I biosynthetic process
GO:0051085 chaperone cofactor-dependent protein refolding
GO:0051135 positive regulation of NK T cell activation
GO:0070062 extracellular exosome
GO:0071682 endocytic vesicle lumen
GO:1900034 regulation of cellular response to heat

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR013126 Heat shock protein 70 familyFamilyFamily
IPR018181 Heat shock protein 70, conserved siteSiteConserved site
IPR029047 Heat shock protein 70kD, peptide-binding domain superfamilyFamilyHomologous superfamily
IPR029048 Heat shock protein 70kD, C-terminal domain superfamilyFamilyHomologous superfamily
IPR042053 HSPH1, nucleotide-binding domainDomainDomain
IPR043129 ATPase, nucleotide binding domainFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB12695 Phenethyl IsothiocyanateDrugbanksmall molecule