Entity Details

Primary name OPRX_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP35377
EntryNameOPRX_MOUSE
FullNameNociceptin receptor
TaxID10090
Evidenceevidence at transcript level
Length367
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesOprl1

GO terms

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GOName
GO:0001626 nociceptin receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005887 integral component of plasma membrane
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0008022 protein C-terminus binding
GO:0016020 membrane
GO:0019233 sensory perception of pain
GO:0031410 cytoplasmic vesicle
GO:0035810 positive regulation of urine volume
GO:0038003 G protein-coupled opioid receptor signaling pathway
GO:0042277 peptide binding
GO:0042755 eating behavior
GO:0042923 neuropeptide binding
GO:0043005 neuron projection
GO:0043951 negative regulation of cAMP-mediated signaling
GO:0045776 negative regulation of blood pressure
GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
GO:0051930 regulation of sensory perception of pain
GO:0060454 positive regulation of gastric acid secretion
GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:1901386 negative regulation of voltage-gated calcium channel activity
GO:1904058 positive regulation of sensory perception of pain
GO:1904059 regulation of locomotor rhythm
GO:1990708 conditioned place preference

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001418 Opioid receptorFamilyFamily
IPR001420 X opioid receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

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