Entity Details

Primary name GCN1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92616
EntryNameGCN1_HUMAN
FullNameeIF-2-alpha kinase activator GCN1
TaxID9606
Evidenceevidence at protein level
Length2671
SequenceStatuscomplete
DateCreated2005-03-01
DateModified2021-06-02

Ontological Relatives

GenesGCN1

GO terms

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GOName
GO:0003723 RNA binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005844 polysome
GO:0008135 translation factor activity, RNA binding
GO:0016020 membrane
GO:0019887 protein kinase regulator activity
GO:0019901 protein kinase binding
GO:0033674 positive regulation of kinase activity
GO:0034198 cellular response to amino acid starvation
GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0043022 ribosome binding
GO:0045296 cadherin binding
GO:1990253 cellular response to leucine starvation

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR021133 HEAT, type 2RepeatRepeat
IPR033173 Translational activator Gcn1FamilyFamily
IPR034085 TOG domainDomainDomain

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink