Entity Details

Primary name PGTA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92696
EntryNamePGTA_HUMAN
FullNameGeranylgeranyl transferase type-2 subunit alpha
TaxID9606
Evidenceevidence at protein level
Length567
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesRABGGTA

GO terms

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GOName
GO:0004663 Rab geranylgeranyltransferase activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005968 Rab-protein geranylgeranyltransferase complex
GO:0006464 cellular protein modification process
GO:0007601 visual perception
GO:0008270 zinc ion binding
GO:0018344 protein geranylgeranylation
GO:0031267 small GTPase binding
GO:0042981 regulation of apoptotic process
GO:0043687 post-translational protein modification

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001611 Leucine-rich repeatRepeatRepeat
IPR002088 Protein prenyltransferase, alpha subunitRepeatRepeat
IPR009087 Rab geranylgeranyltransferase, alpha subunit, insert-domainDomainDomain
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR032955 Geranylgeranyl transferase type-2 subunit alphaFamilyFamily
IPR036254 Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04464 N-FormylmethionineDrugbanksmall molecule
DB07780 Farnesyl diphosphateDrugbanksmall molecule
DB07841 Geranylgeranyl diphosphateDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PGTA_HUMANNAC1_MOUSEbhf-ucl, BioGRID28755400 details