Entity Details

Primary name KAT2A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92830
EntryNameKAT2A_HUMAN
FullNameHistone acetyltransferase KAT2A
TaxID9606
Evidenceevidence at protein level
Length837
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesKAT2A

GO terms

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GOName
GO:0000123 histone acetyltransferase complex
GO:0000785 chromatin
GO:0001701 in utero embryonic development
GO:0001756 somitogenesis
GO:0001819 positive regulation of cytokine production
GO:0001843 neural tube closure
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0004402 histone acetyltransferase activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0006338 chromatin remodeling
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007507 heart development
GO:0007616 long-term memory
GO:0008134 transcription factor binding
GO:0008283 cell population proliferation
GO:0010484 H3 histone acetyltransferase activity
GO:0014070 response to organic cyclic compound
GO:0016032 viral process
GO:0016573 histone acetylation
GO:0016578 histone deubiquitination
GO:0016579 protein deubiquitination
GO:0018393 internal peptidyl-lysine acetylation
GO:0019903 protein phosphatase binding
GO:0021537 telencephalon development
GO:0022037 metencephalon development
GO:0030901 midbrain development
GO:0030914 STAGA complex
GO:0031346 positive regulation of cell projection organization
GO:0031647 regulation of protein stability
GO:0031667 response to nutrient levels
GO:0033276 transcription factor TFTC complex
GO:0035066 positive regulation of histone acetylation
GO:0035264 multicellular organism growth
GO:0042826 histone deacetylase binding
GO:0043966 histone H3 acetylation
GO:0043997 histone acetyltransferase activity (H4-K12 specific)
GO:0044154 histone H3-K14 acetylation
GO:0045589 regulation of regulatory T cell differentiation
GO:0045722 positive regulation of gluconeogenesis
GO:0045815 positive regulation of gene expression, epigenetic
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046600 negative regulation of centriole replication
GO:0048167 regulation of synaptic plasticity
GO:0048312 intracellular distribution of mitochondria
GO:0050863 regulation of T cell activation
GO:0060173 limb development
GO:0061035 regulation of cartilage development
GO:0061733 peptide-lysine-N-acetyltransferase activity
GO:0071356 cellular response to tumor necrosis factor
GO:0071929 alpha-tubulin acetylation
GO:0072686 mitotic spindle
GO:0106077 histone succinylation
GO:0106078 histone succinyltransferase activity
GO:0106227 peptidyl-lysine glutarylation
GO:0106229 histone glutaryltransferase activity
GO:1903010 regulation of bone development
GO:1990090 cellular response to nerve growth factor stimulus
GO:2000036 regulation of stem cell population maintenance
GO:2000727 positive regulation of cardiac muscle cell differentiation

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000182 GNAT domainDomainDomain
IPR001487 BromodomainDomainDomain
IPR009464 PCAF, N-terminalDomainDomain
IPR016181 Acyl-CoA N-acyltransferaseFamilyHomologous superfamily
IPR016376 Histone acetyltransferase GCN5/PCAFFamilyFamily
IPR018359 Bromodomain, conserved siteSiteConserved site
IPR036427 Bromodomain-like superfamilyFamilyHomologous superfamily
IPR037800 Histone acetyltransferase GCN5FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01992 Coenzyme ADrugbanksmall molecule

Interactions

3 interactions