Entity Details

Primary name CASPA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92851
EntryNameCASPA_HUMAN
FullNameCaspase-10
TaxID9606
Evidenceevidence at protein level
Length521
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesCASP10

GO terms

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GOName
GO:0004197 cysteine-type endopeptidase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007166 cell surface receptor signaling pathway
GO:0031265 CD95 death-inducing signaling complex
GO:0031625 ubiquitin protein ligase binding
GO:0035877 death effector domain binding
GO:0042981 regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process
GO:0097190 apoptotic signaling pathway
GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:0097342 ripoptosome

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001309 Peptidase C14, p20 domainDomainDomain
IPR001875 Death effector domainDomainDomain
IPR002138 Peptidase C14, caspase non-catalytic subunit p10DomainDomain
IPR002398 Peptidase C14 familyFamilyFamily
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR015917 Peptidase C14A, caspase catalytic domainDomainDomain
IPR016129 Peptidase family C14A, His active siteSiteActive site
IPR029030 Caspase-like domain superfamilyFamilyHomologous superfamily
IPR033139 Peptidase family C14A, cysteine active siteSiteActive site
IPR035701 Caspase-10FamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CASPA_HUMANTRAF2_MOUSEIntAct12884866 details
CASPA_HUMANFADD_MOUSEIntAct12884866 details