Entity Details

Primary name CSN5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92905
EntryNameCSN5_HUMAN
FullNameCOP9 signalosome complex subunit 5
TaxID9606
Evidenceevidence at protein level
Length334
SequenceStatuscomplete
DateCreated2004-11-23
DateModified2021-06-02

Ontological Relatives

GenesCOPS5

GO terms

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GOName
GO:0000338 protein deneddylation
GO:0000715 nucleotide-excision repair, DNA damage recognition
GO:0003713 transcription coactivator activity
GO:0003743 translation initiation factor activity
GO:0004222 metalloendopeptidase activity
GO:0004843 thiol-dependent deubiquitinase
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006412 translation
GO:0008021 synaptic vesicle
GO:0008180 COP9 signalosome
GO:0008237 metallopeptidase activity
GO:0016579 protein deubiquitination
GO:0019784 NEDD8-specific protease activity
GO:0019899 enzyme binding
GO:0035718 macrophage migration inhibitory factor binding
GO:0043066 negative regulation of apoptotic process
GO:0043687 post-translational protein modification
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046328 regulation of JNK cascade
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051726 regulation of cell cycle
GO:0070122 isopeptidase activity
GO:1903894 regulation of IRE1-mediated unfolded protein response
GO:1990182 exosomal secretion

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle
Nucleus

Domains

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DomainNameCategoryType
IPR000555 JAB1/MPN/MOV34 metalloenzyme domainDomainDomain
IPR037518 MPN domainDomainDomain
IPR037740 COP9 signalosome complex subunit 5FamilyFamily
IPR040961 Cop9 signalosome subunit 5 C-terminal domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CSN5_HUMANHIF1A_MOUSEBioGRID11707426 details
CSN5_HUMANCSN6_MOUSEBioGRID22956996 details