Entity Details

Primary name KAT5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92993
EntryNameKAT5_HUMAN
FullNameHistone acetyltransferase KAT5
TaxID9606
Evidenceevidence at protein level
Length513
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesKAT5

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000729 DNA double-strand break processing
GO:0000812 Swr1 complex
GO:0003712 transcription coregulator activity
GO:0003713 transcription coactivator activity
GO:0004402 histone acetyltransferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005730 nucleolus
GO:0006260 DNA replication
GO:0006302 double-strand break repair
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0010212 response to ionizing radiation
GO:0010508 positive regulation of autophagy
GO:0016032 viral process
GO:0016573 histone acetylation
GO:0018394 peptidyl-lysine acetylation
GO:0032703 negative regulation of interleukin-2 production
GO:0032777 Piccolo NuA4 histone acetyltransferase complex
GO:0035267 NuA4 histone acetyltransferase complex
GO:0040008 regulation of growth
GO:0042393 histone binding
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0061733 peptide-lysine-N-acetyltransferase activity
GO:0071392 cellular response to estradiol stimulus
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1901985 positive regulation of protein acetylation
GO:1904837 beta-catenin-TCF complex assembly

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000953 Chromo/chromo shadow domainDomainDomain
IPR002717 Histone acetyltransferase domain, MYST-typeDomainDomain
IPR016181 Acyl-CoA N-acyltransferaseFamilyHomologous superfamily
IPR016197 Chromo-like domain superfamilyFamilyHomologous superfamily
IPR025995 RNA binding activity-knot of a chromodomainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037995 Histone acetyltransferase KAT5/Tip60FamilyFamily
IPR040706 MYST, zinc finger domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01992 Coenzyme ADrugbanksmall molecule
DB02039 S-Acetyl-CysteineDrugbanksmall molecule

Interactions

4 interactions