Entity Details

Primary name UBP7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ93009
EntryNameUBP7_HUMAN
FullNameUbiquitin carboxyl-terminal hydrolase 7
TaxID9606
Evidenceevidence at protein level
Length1102
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesUSP7

GO terms

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GOName
GO:0002039 p53 binding
GO:0004197 cysteine-type endopeptidase activity
GO:0004843 thiol-dependent deubiquitinase
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol
GO:0006111 regulation of gluconeogenesis
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007275 multicellular organism development
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0010216 maintenance of DNA methylation
GO:0016032 viral process
GO:0016567 protein ubiquitination
GO:0016579 protein deubiquitination
GO:0016604 nuclear body
GO:0016605 PML body
GO:0031625 ubiquitin protein ligase binding
GO:0031647 regulation of protein stability
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032991 protein-containing complex
GO:0035520 monoubiquitinated protein deubiquitination
GO:0035616 histone H2B conserved C-terminal lysine deubiquitination
GO:0042752 regulation of circadian rhythm
GO:0048511 rhythmic process
GO:0050821 protein stabilization
GO:0051090 regulation of DNA-binding transcription factor activity
GO:0070536 protein K63-linked deubiquitination
GO:0101005 deubiquitinase activity
GO:1901537 positive regulation of DNA demethylation
GO:1901796 regulation of signal transduction by p53 class mediator
GO:1904353 regulation of telomere capping
GO:1905279 regulation of retrograde transport, endosome to Golgi
GO:1990380 Lys48-specific deubiquitinase activity

Subcellular Location

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Subcellular Location
Chromosome
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolaseDomainDomain
IPR002083 MATH/TRAF domainDomainDomain
IPR008974 TRAF-likeFamilyHomologous superfamily
IPR018200 Ubiquitin specific protease, conserved siteSiteConserved site
IPR024729 Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domainDomainDomain
IPR028889 Ubiquitin specific protease domainDomainDomain
IPR029346 Ubiquitin carboxyl-terminal hydrolase, C-terminalDomainDomain
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily

Diseases

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