Entity Details

Primary name RFC1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP35601
EntryNameRFC1_MOUSE
FullNameReplication factor C subunit 1
TaxID10090
Evidenceevidence at protein level
Length1131
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesRfc1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0003690 double-stranded DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005663 DNA replication factor C complex
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0019904 protein domain specific binding
GO:0031391 Elg1 RFC-like complex
GO:0032991 protein-containing complex
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0061860 DNA clamp unloader activity
GO:0090618 DNA clamp unloading

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001357 BRCT domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR003959 ATPase, AAA-type, coreDomainDomain
IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminalFamilyHomologous superfamily
IPR012178 Replication factor C subunit 1FamilyFamily
IPR013725 DNA replication factor RFC1, C-terminalDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036420 BRCT domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
RFC1_MOUSEUBC_MOUSEBioGRID28190767 details
RFC1_MOUSEOTUD4_HUMANBioGRID31138677 details