Entity Details

Primary name AP2M1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96CW1
EntryNameAP2M1_HUMAN
FullNameAP-2 complex subunit mu
TaxID9606
Evidenceevidence at protein level
Length435
SequenceStatuscomplete
DateCreated2004-08-16
DateModified2021-06-02

Ontological Relatives

GenesAP2M1

GO terms

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GOName
GO:0005048 signal sequence binding
GO:0005765 lysosomal membrane
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005905 clathrin-coated pit
GO:0006886 intracellular protein transport
GO:0006897 endocytosis
GO:0006900 vesicle budding from membrane
GO:0008289 lipid binding
GO:0016192 vesicle-mediated transport
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030122 AP-2 adaptor complex
GO:0030666 endocytic vesicle membrane
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0031623 receptor internalization
GO:0032802 low-density lipoprotein particle receptor catabolic process
GO:0034383 low-density lipoprotein particle clearance
GO:0034622 cellular protein-containing complex assembly
GO:0035615 clathrin adaptor activity
GO:0036020 endolysosome membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0044325 transmembrane transporter binding
GO:0045334 clathrin-coated endocytic vesicle
GO:0048013 ephrin receptor signaling pathway
GO:0050690 regulation of defense response to virus by virus
GO:0050750 low-density lipoprotein particle receptor binding
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0061024 membrane organization
GO:0070062 extracellular exosome
GO:0072583 clathrin-dependent endocytosis
GO:0097494 regulation of vesicle size
GO:1903077 negative regulation of protein localization to plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane
Membrane

Domains

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DomainNameCategoryType
IPR001392 Clathrin adaptor, mu subunitFamilyFamily
IPR011012 Longin-like domain superfamilyFamilyHomologous superfamily
IPR018240 Clathrin adaptor, mu subunit, conserved siteSiteConserved site
IPR022775 AP complex, mu/sigma subunitDomainDomain
IPR028565 Mu homology domainDomainDomain
IPR036168 AP-2 complex subunit mu, C-terminal superfamilyFamilyHomologous superfamily
IPR043512 Mu2, C-terminal domainDomainDomain
IPR043532 AP-2 complex subunit mu, N-terminalDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
AP2M1_HUMANRN111_MOUSEBioGRID20965945 details