Entity Details

Primary name RNF31_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96EP0
EntryNameRNF31_HUMAN
FullNameE3 ubiquitin-protein ligase RNF31
TaxID9606
Evidenceevidence at protein level
Length1072
SequenceStatuscomplete
DateCreated2004-03-15
DateModified2021-06-02

Ontological Relatives

GenesRNF31

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0004842 ubiquitin-protein transferase activity
GO:0005829 cytosol
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0009898 cytoplasmic side of plasma membrane
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway
GO:0023035 CD40 signaling pathway
GO:0031625 ubiquitin protein ligase binding
GO:0035631 CD40 receptor complex
GO:0042802 identical protein binding
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 ubiquitin binding
GO:0046872 metal ion binding
GO:0050852 T cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0071797 LUBAC complex
GO:0097039 protein linear polyubiquitination
GO:1903955 positive regulation of protein targeting to mitochondrion

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001876 Zinc finger, RanBP2-typeDomainDomain
IPR002867 IBR domainDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR015940 Ubiquitin-associated domainDomainDomain
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR018997 PUB domainDomainDomain
IPR026254 E3 ubiquitin-protein ligase RNF31-likeFamilyFamily
IPR032065 E3 ubiquitin-protein ligase RNF31, UBA-like domainDomainDomain
IPR036339 PUB-like domain superfamilyFamilyHomologous superfamily
IPR036443 Zinc finger, RanBP2-type superfamilyFamilyHomologous superfamily
IPR040641 E3 ubiquitin-protein ligase RNF31, PUB domainDomainDomain
IPR041031 RNF31, C-terminalDomainDomain
IPR044066 TRIAD supradomainDomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
RNF31_HUMANNEMO_MOUSEBioGRID, MINT24469399 details
RNF31_HUMANAZI2_MOUSEIntAct21903422 details
RNF31_HUMANCAR11_MOUSEBioGRID31391255 details