Entity Details

Primary name BMR1A_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP36895
EntryNameBMR1A_MOUSE
FullNameBone morphogenetic protein receptor type-1A
TaxID10090
Evidenceevidence at protein level
Length532
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesBmpr1a

GO terms

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GOName
GO:0001649 osteoblast differentiation
GO:0001701 in utero embryonic development
GO:0001707 mesoderm formation
GO:0001756 somitogenesis
GO:0001880 Mullerian duct regression
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0002062 chondrocyte differentiation
GO:0003007 heart morphogenesis
GO:0003148 outflow tract septum morphogenesis
GO:0003151 outflow tract morphogenesis
GO:0003161 cardiac conduction system development
GO:0003171 atrioventricular valve development
GO:0003183 mitral valve morphogenesis
GO:0003186 tricuspid valve morphogenesis
GO:0003203 endocardial cushion morphogenesis
GO:0003215 cardiac right ventricle morphogenesis
GO:0003222 ventricular trabecula myocardium morphogenesis
GO:0003223 ventricular compact myocardium morphogenesis
GO:0003272 endocardial cushion formation
GO:0004674 protein serine/threonine kinase activity
GO:0005025 transforming growth factor beta receptor activity, type I
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005901 caveola
GO:0006468 protein phosphorylation
GO:0006955 immune response
GO:0007389 pattern specification process
GO:0007398 ectoderm development
GO:0007399 nervous system development
GO:0007492 endoderm development
GO:0007507 heart development
GO:0009897 external side of plasma membrane
GO:0009950 dorsal/ventral axis specification
GO:0009952 anterior/posterior pattern specification
GO:0009953 dorsal/ventral pattern formation
GO:0009986 cell surface
GO:0010629 negative regulation of gene expression
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0014032 neural crest cell development
GO:0014912 negative regulation of smooth muscle cell migration
GO:0016021 integral component of membrane
GO:0019827 stem cell population maintenance
GO:0021983 pituitary gland development
GO:0021998 neural plate mediolateral regionalization
GO:0030154 cell differentiation
GO:0030324 lung development
GO:0030425 dendrite
GO:0030501 positive regulation of bone mineralization
GO:0030509 BMP signaling pathway
GO:0032915 positive regulation of transforming growth factor beta2 production
GO:0035137 hindlimb morphogenesis
GO:0035912 dorsal aorta morphogenesis
GO:0036122 BMP binding
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042733 embryonic digit morphogenesis
GO:0042803 protein homodimerization activity
GO:0043025 neuronal cell body
GO:0043235 receptor complex
GO:0045669 positive regulation of osteoblast differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046332 SMAD binding
GO:0046872 metal ion binding
GO:0048339 paraxial mesoderm development
GO:0048352 paraxial mesoderm structural organization
GO:0048368 lateral mesoderm development
GO:0048378 regulation of lateral mesodermal cell fate specification
GO:0048382 mesendoderm development
GO:0048568 embryonic organ development
GO:0048589 developmental growth
GO:0048598 embryonic morphogenesis
GO:0050679 positive regulation of epithelial cell proliferation
GO:0050768 negative regulation of neurogenesis
GO:0051148 negative regulation of muscle cell differentiation
GO:0051216 cartilage development
GO:0060021 roof of mouth development
GO:0060043 regulation of cardiac muscle cell proliferation
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060391 positive regulation of SMAD protein signal transduction
GO:0060412 ventricular septum morphogenesis
GO:0060896 neural plate pattern specification
GO:0060914 heart formation
GO:0060928 atrioventricular node cell development
GO:0061312 BMP signaling pathway involved in heart development
GO:0061626 pharyngeal arch artery morphogenesis
GO:0071363 cellular response to growth factor stimulus
GO:0071773 cellular response to BMP stimulus
GO:0098821 BMP receptor activity
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1904414 positive regulation of cardiac ventricle development
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:1905285 fibrous ring of heart morphogenesis
GO:2000772 regulation of cellular senescence

Subcellular Location

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Subcellular Location
Cell membrane
Cell surface

Domains

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DomainNameCategoryType
IPR000333 Ser/Thr protein kinase, TGFB receptorFamilyFamily
IPR000472 Activin types I and II receptor domainDomainDomain
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR003605 GS domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
BMR1A_MOUSESMAD7_MOUSEBioGRID20663871 details
BMR1A_MOUSESMAD6_MOUSEBioGRID20663871 details