Entity Details

Primary name THB_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP37242
EntryNameTHB_MOUSE
FullNameThyroid hormone receptor beta
TaxID10090
Evidenceevidence at protein level
Length461
SequenceStatuscomplete
DateCreated1994-10-01
DateModified2021-06-02

Ontological Relatives

GenesThrb

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0002154 thyroid hormone mediated signaling pathway
GO:0003682 chromatin binding
GO:0003690 double-stranded DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007605 sensory perception of sound
GO:0007621 negative regulation of female receptivity
GO:0008016 regulation of heart contraction
GO:0008050 female courtship behavior
GO:0008270 zinc ion binding
GO:0008284 positive regulation of cell population proliferation
GO:0009755 hormone-mediated signaling pathway
GO:0009887 animal organ morphogenesis
GO:0016604 nuclear body
GO:0019216 regulation of lipid metabolic process
GO:0019899 enzyme binding
GO:0030154 cell differentiation
GO:0031490 chromatin DNA binding
GO:0032332 positive regulation of chondrocyte differentiation
GO:0042802 identical protein binding
GO:0045778 positive regulation of ossification
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046549 retinal cone cell development
GO:0060509 type I pneumocyte differentiation
GO:0070324 thyroid hormone binding
GO:0090181 regulation of cholesterol metabolic process
GO:0090207 regulation of triglyceride metabolic process
GO:0097067 cellular response to thyroid hormone stimulus
GO:0097474 retinal cone cell apoptotic process
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR001728 Thyroid hormone receptorFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

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