Entity Details

Primary name HMGCL_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP38060
EntryNameHMGCL_MOUSE
FullNameHydroxymethylglutaryl-CoA lyase, mitochondrial
TaxID10090
Evidenceevidence at protein level
Length325
SequenceStatuscomplete
DateCreated1994-10-01
DateModified2021-06-02

Ontological Relatives

GenesHmgcl

GO terms

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GOName
GO:0000062 fatty-acyl-CoA binding
GO:0000287 magnesium ion binding
GO:0001889 liver development
GO:0004419 hydroxymethylglutaryl-CoA lyase activity
GO:0005198 structural molecule activity
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005777 peroxisome
GO:0006552 leucine catabolic process
GO:0006629 lipid metabolic process
GO:0006637 acyl-CoA metabolic process
GO:0007005 mitochondrion organization
GO:0007584 response to nutrient
GO:0030145 manganese ion binding
GO:0031406 carboxylic acid binding
GO:0032991 protein-containing complex
GO:0042594 response to starvation
GO:0046872 metal ion binding
GO:0046951 ketone body biosynthetic process
GO:0070542 response to fatty acid

Subcellular Location

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Subcellular Location
Mitochondrion matrix
Peroxisome

Domains

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DomainNameCategoryType
IPR000138 Hydroxymethylglutaryl-CoA lyase, active siteSiteActive site
IPR000891 Pyruvate carboxyltransferaseDomainDomain
IPR013785 Aldolase-type TIM barrelFamilyHomologous superfamily
IPR043594 HMG-CoA lyaseFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
HMGCL_MOUSEHCD2_HUMANBioGRID22496890 details