Entity Details

Primary name EHMT2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96KQ7
EntryNameEHMT2_HUMAN
FullNameHistone-lysine N-methyltransferase EHMT2
TaxID9606
Evidenceevidence at protein level
Length1210
SequenceStatuscomplete
DateCreated2002-11-15
DateModified2021-06-02

Ontological Relatives

GenesEHMT2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0002039 p53 binding
GO:0005654 nucleoplasm
GO:0016607 nuclear speck
GO:0034968 histone lysine methylation
GO:0046976 histone methyltransferase activity (H3-K27 specific)
GO:0070742 C2H2 zinc finger domain binding
GO:0000785 chromatin
GO:0006275 regulation of DNA replication
GO:0008270 zinc ion binding
GO:0009267 cellular response to starvation
GO:0016279 protein-lysine N-methyltransferase activity
GO:0016571 histone methylation
GO:0018027 peptidyl-lysine dimethylation
GO:0006306 DNA methylation
GO:0018024 histone-lysine N-methyltransferase activity
GO:0046974 histone methyltransferase activity (H3-K9 specific)
GO:0070317 negative regulation of G0 to G1 transition
GO:1990841 promoter-specific chromatin binding
GO:0005634 nucleus
GO:1901796 regulation of signal transduction by p53 class mediator

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001214 SET domainDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR007728 Pre-SET domainDomainDomain
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR038034 Histone-lysine N-methyltransferase EHMT2FamilyFamily
IPR043550 Histone-lysine N-methyltransferase EHMT1/EHMT2FamilyFamily

Diseases

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Interactions

4 interactions