Entity Details

Primary name DYN2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP39054
EntryNameDYN2_MOUSE
FullNameDynamin-2
TaxID10090
Evidenceevidence at protein level
Length870
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesDnm2

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0000266 mitochondrial fission
GO:0001891 phagocytic cup
GO:0001917 photoreceptor inner segment
GO:0002031 G protein-coupled receptor internalization
GO:0003281 ventricular septum development
GO:0003374 dynamin family protein polymerization involved in mitochondrial fission
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005794 Golgi apparatus
GO:0005802 trans-Golgi network
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0005905 clathrin-coated pit
GO:0006893 Golgi to plasma membrane transport
GO:0006898 receptor-mediated endocytosis
GO:0006909 phagocytosis
GO:0008017 microtubule binding
GO:0010592 positive regulation of lamellipodium assembly
GO:0014069 postsynaptic density
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane
GO:0017124 SH3 domain binding
GO:0019901 protein kinase binding
GO:0030027 lamellipodium
GO:0030054 cell junction
GO:0030424 axon
GO:0030496 midbody
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030516 regulation of axon extension
GO:0030670 phagocytic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0031623 receptor internalization
GO:0031749 D2 dopamine receptor binding
GO:0031966 mitochondrial membrane
GO:0032587 ruffle membrane
GO:0032991 protein-containing complex
GO:0033572 transferrin transport
GO:0035020 regulation of Rac protein signal transduction
GO:0035904 aorta development
GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding
GO:0044327 dendritic spine head
GO:0044351 macropinocytosis
GO:0044877 protein-containing complex binding
GO:0045211 postsynaptic membrane
GO:0045334 clathrin-coated endocytic vesicle
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0045807 positive regulation of endocytosis
GO:0048471 perinuclear region of cytoplasm
GO:0048488 synaptic vesicle endocytosis
GO:0048812 neuron projection morphogenesis
GO:0050699 WW domain binding
GO:0050766 positive regulation of phagocytosis
GO:0050803 regulation of synapse structure or activity
GO:0050998 nitric-oxide synthase binding
GO:0060976 coronary vasculature development
GO:0061025 membrane fusion
GO:0098793 presynapse
GO:0098844 postsynaptic endocytic zone membrane
GO:0098884 postsynaptic neurotransmitter receptor internalization
GO:0098978 glutamatergic synapse
GO:0099092 postsynaptic density, intracellular component
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1902856 negative regulation of non-motile cilium assembly
GO:1903351 cellular response to dopamine
GO:1903358 regulation of Golgi organization
GO:1903408 positive regulation of P-type sodium:potassium-exchanging transporter activity
GO:1903526 negative regulation of membrane tubulation
GO:2000370 positive regulation of clathrin-dependent endocytosis

Subcellular Location

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Subcellular Location
Cell junction
Cell projection
Cytoplasm
Cytoplasmic vesicle
Membrane
Midbody

Domains

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DomainNameCategoryType
IPR000375 Dynamin stalk domainDomainDomain
IPR001401 Dynamin, GTPase domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR003130 Dynamin GTPase effectorDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR019762 Dynamin, GTPase region, conserved siteSiteConserved site
IPR020850 GTPase effector domainDomainDomain
IPR022812 DynaminFamilyFamily
IPR027188 Dynamin-2FamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR030381 Dynamin-type guanine nucleotide-binding (G) domainDomainDomain

Diseases

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