Entity Details

Primary name GRIK2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP39087
EntryNameGRIK2_MOUSE
FullNameGlutamate receptor ionotropic, kainate 2
TaxID10090
Evidenceevidence at protein level
Length908
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0001662 behavioral fear response
GO:0004970 ionotropic glutamate receptor activity
GO:0005234 extracellularly glutamate-gated ion channel activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006874 cellular calcium ion homeostasis
GO:0006886 intracellular protein transport
GO:0007268 chemical synaptic transmission
GO:0008066 glutamate receptor activity
GO:0008328 ionotropic glutamate receptor complex
GO:0014069 postsynaptic density
GO:0015276 ligand-gated ion channel activity
GO:0015277 kainate selective glutamate receptor activity
GO:0016020 membrane
GO:0019228 neuronal action potential
GO:0030165 PDZ domain binding
GO:0030424 axon
GO:0030425 dendrite
GO:0031624 ubiquitin conjugating enzyme binding
GO:0031625 ubiquitin protein ligase binding
GO:0032839 dendrite cytoplasm
GO:0032983 kainate selective glutamate receptor complex
GO:0035249 synaptic transmission, glutamatergic
GO:0038023 signaling receptor activity
GO:0042391 regulation of membrane potential
GO:0042734 presynaptic membrane
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043113 receptor clustering
GO:0043195 terminal bouton
GO:0043204 perikaryon
GO:0043524 negative regulation of neuron apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0046328 regulation of JNK cascade
GO:0048169 regulation of long-term neuronal synaptic plasticity
GO:0048172 regulation of short-term neuronal synaptic plasticity
GO:0050804 modulation of chemical synaptic transmission
GO:0050806 positive regulation of synaptic transmission
GO:0051402 neuron apoptotic process
GO:0051967 negative regulation of synaptic transmission, glutamatergic
GO:0060079 excitatory postsynaptic potential
GO:0060080 inhibitory postsynaptic potential
GO:0098686 hippocampal mossy fiber to CA3 synapse
GO:0098794 postsynapse
GO:0098978 glutamatergic synapse
GO:0099507 ligand-gated ion channel activity involved in regulation of presynaptic membrane potential
GO:0120169 detection of cold stimulus involved in thermoception
GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR001320 Ionotropic glutamate receptorDomainDomain
IPR001508 Ionotropic glutamate receptor, metazoaFamilyFamily
IPR001828 Receptor, ligand binding regionDomainDomain
IPR019594 Ionotropic glutamate receptor, L-glutamate and glycine-binding domainDomainDomain
IPR028082 Periplasmic binding protein-like IFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
GRIK2_MOUSEEGFLA_MOUSEUniProt18641643 details