Entity Details

Primary name TRAF1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP39428
EntryNameTRAF1_MOUSE
FullNameTNF receptor-associated factor 1
TaxID10090
Evidenceevidence at protein level
Length409
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesTraf1

GO terms

Show/Hide Table
GOName
GO:0005164 tumor necrosis factor receptor binding
GO:0005737 cytoplasm
GO:0006915 apoptotic process
GO:0008270 zinc ion binding
GO:0009898 cytoplasmic side of plasma membrane
GO:0031625 ubiquitin protein ligase binding
GO:0031996 thioesterase binding
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0042802 identical protein binding
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046330 positive regulation of JNK cascade
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0070534 protein K63-linked ubiquitination
GO:2001236 regulation of extrinsic apoptotic signaling pathway

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR002083 MATH/TRAF domainDomainDomain
IPR008974 TRAF-likeFamilyHomologous superfamily
IPR012227 TNF receptor-associated factor TRAF, metazoaFamilyFamily
IPR027136 TNF receptor-associated factor 1FamilyFamily
IPR032070 TNF receptor-associated factor, BIRC3 binding domainDomainDomain
IPR037306 TNF receptor-associated factor 1, MATH domainDomainDomain
IPR043211 TNF receptor-associated factor TRAFFamilyFamily

Diseases

Show/Hide Table

Interactions

38 interactions

InteractorPartnerSourcesPublicationsLink
TRAF1_MOUSETNR9_MOUSEIntAct9418902 details
TRAF1_MOUSETNR4_MOUSEIntAct9418902 details
TRAF1_MOUSETNR8_HUMANBioGRID, IntAct8627180 details
TRAF1_MOUSETF7L2_MOUSEIntAct15102471 details
TRAF1_MOUSEPARP1_MOUSEIntAct15102471 details
TRAF1_MOUSETF7L1_MOUSEIntAct15102471 details
TRAF1_MOUSETANK_MOUSEIntAct15102471 details
TRAF1_MOUSEPKHN1_MOUSEIntAct15102471 details
TRAF1_MOUSEHM20B_MOUSEIntAct15102471 details
TRAF1_MOUSENUP58_MOUSEIntAct15102471 details
TRAF1_MOUSEIQGA1_MOUSEIntAct15102471 details
TRAF1_MOUSEFKBPL_MOUSEIntAct15102471 details
TRAF1_MOUSEMIRO1_MOUSEIntAct15102471 details
TRAF1_MOUSESIKE1_MOUSEIntAct15102471 details
TRAF1_MOUSERAI14_MOUSEIntAct15102471 details
TRAF1_MOUSEDNJA3_MOUSEIntAct15102471 details
TRAF1_MOUSEDTNB_MOUSEIntAct15102471 details
TRAF1_MOUSEUTP6_MOUSEIntAct15102471 details
TRAF1_MOUSESAHH_MOUSEIntAct15102471 details
TRAF1_MOUSECAR11_MOUSEIntAct15102471 details
TRAF1_MOUSEPPR18_MOUSEIntAct15102471 details
TRAF1_MOUSERCBT1_MOUSEIntAct15102471 details
TRAF1_MOUSEHM20A_MOUSEIntAct15102471 details
TRAF1_MOUSEBANK1_MOUSEIntAct15102471 details
TRAF1_MOUSEZMAT3_MOUSEIntAct15102471 details
TRAF1_MOUSELRSM1_MOUSEIntAct15102471 details
TRAF1_MOUSETRAD1_MOUSEIntAct15102471 details
TRAF1_MOUSESC16A_MOUSEIntAct15102471 details
TRAF1_MOUSERNF31_MOUSEIntAct15102471 details
TRAF1_MOUSEANS4B_MOUSEIntAct15102471 details
TRAF1_MOUSETLE5_MOUSEIntAct15102471 details
TRAF1_MOUSESUN2_MOUSEIntAct15102471 details
TRAF1_MOUSEEDAR_HUMANBioGRID, IntAct11035039 details
TRAF1_MOUSETNR1B_HUMANIntAct8069916 details
TRAF1_MOUSETNR19_HUMANBioGRID10809768 details
TRAF1_MOUSEBIRC2_HUMANBioGRID8548810 details
TRAF1_MOUSETNR6_HUMANBioGRID11035039 details
TRAF1_MOUSETNR1A_HUMANBioGRID11035039 details