Entity Details

Primary name FEN1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP39749
EntryNameFEN1_MOUSE
FullNameFlap endonuclease 1
TaxID10090
Evidenceevidence at protein level
Length378
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0004523 RNA-DNA hybrid ribonuclease activity
GO:0004527 exonuclease activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006284 base-excision repair
GO:0007613 memory
GO:0008409 5'-3' exonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0030145 manganese ion binding
GO:0032991 protein-containing complex
GO:0043137 DNA replication, removal of RNA primer
GO:0045876 positive regulation of sister chromatid cohesion
GO:0048256 flap endonuclease activity
GO:0090305 nucleic acid phosphodiester bond hydrolysis

Subcellular Location

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Subcellular Location
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR006084 XPG/Rad2 endonucleaseFamilyFamily
IPR006085 XPG, N-terminalDomainDomain
IPR006086 XPG-I domainDomainDomain
IPR008918 Helix-hairpin-helix motif, class 2SiteConserved site
IPR019974 XPG conserved siteSiteConserved site
IPR023426 Flap endonuclease 1FamilyFamily
IPR029060 PIN-like domain superfamilyFamilyHomologous superfamily
IPR036279 5'-3' exonuclease, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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