Entity Details

Primary name DOCK7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96N67
EntryNameDOCK7_HUMAN
FullNameDedicator of cytokinesis protein 7
TaxID9606
Evidenceevidence at protein level
Length2140
SequenceStatuscomplete
DateCreated2003-07-03
DateModified2021-06-02

Ontological Relatives

GenesDOCK7

GO terms

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GOName
GO:0000226 microtubule cytoskeleton organization
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005925 focal adhesion
GO:0007264 small GTPase mediated signal transduction
GO:0007409 axonogenesis
GO:0022027 interkinetic nuclear migration
GO:0030424 axon
GO:0030426 growth cone
GO:0031175 neuron projection development
GO:0031267 small GTPase binding
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0043005 neuron projection
GO:0045178 basal part of cell
GO:0045200 establishment of neuroblast polarity
GO:0050767 regulation of neurogenesis
GO:0090630 activation of GTPase activity
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1904754 positive regulation of vascular associated smooth muscle cell migration

Subcellular Location

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Subcellular Location
Cell projection

Domains

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DomainNameCategoryType
IPR021816 Dedicator of cytokinesis C/D, N-terminalDomainDomain
IPR026791 Dedicator of cytokinesisFamilyFamily
IPR027007 C2 DOCK-type domainDomainDomain
IPR027357 DOCKER domainDomainDomain
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR037808 Dedicator of cytokinesis C, C2 domainDomainDomain
IPR043161 Dedicator of cytokinesis, C-terminal, lobe AFamilyHomologous superfamily
IPR043162 Dedicator of cytokinesis, C-terminal, lobe CFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
DOCK7_HUMANRHG30_MOUSEIntAct32203420 details
DOCK7_HUMANOSTM1_MOUSEBioGRID26598607 details