Entity Details

Primary name MUS81_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96NY9
EntryNameMUS81_HUMAN
FullNameCrossover junction endonuclease MUS81
TaxID9606
Evidenceevidence at protein level
Length551
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesMUS81

GO terms

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GOName
GO:0000712 resolution of meiotic recombination intermediates
GO:0000727 double-strand break repair via break-induced replication
GO:0000737 DNA catabolic process, endonucleolytic
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0006281 DNA repair
GO:0031573 mitotic intra-S DNA damage checkpoint signaling
GO:0033687 osteoblast proliferation
GO:0036297 interstrand cross-link repair
GO:0046872 metal ion binding
GO:0048257 3'-flap endonuclease activity
GO:0048476 Holliday junction resolvase complex
GO:0072429 response to intra-S DNA damage checkpoint signaling

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR006166 ERCC4 domainDomainDomain
IPR011335 Restriction endonuclease type II-likeFamilyHomologous superfamily
IPR027421 DNA polymerase lambda lyase domain superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
MUS81_HUMANSLX4_MOUSEBioGRID25224045 25722289 details