Entity Details

Primary name MCCA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96RQ3
EntryNameMCCA_HUMAN
FullNameMethylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length725
SequenceStatuscomplete
DateCreated2002-03-05
DateModified2021-06-02

Ontological Relatives

GenesMCCC1

GO terms

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GOName
GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial
GO:0004075 biotin carboxylase activity
GO:0004485 methylcrotonoyl-CoA carboxylase activity
GO:0005524 ATP binding
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006552 leucine catabolic process
GO:0006768 biotin metabolic process
GO:0009083 branched-chain amino acid catabolic process
GO:0009374 biotin binding
GO:0016421 CoA carboxylase activity
GO:0046872 metal ion binding
GO:1905202 methylcrotonoyl-CoA carboxylase complex

Subcellular Location

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Subcellular Location
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR000089 Biotin/lipoyl attachmentDomainDomain
IPR001882 Biotin-binding siteSiteBinding site
IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domainDomainDomain
IPR005481 Biotin carboxylase-like, N-terminal domainDomainDomain
IPR005482 Biotin carboxylase, C-terminalDomainDomain
IPR011053 Single hybrid motifFamilyHomologous superfamily
IPR011054 Rudiment single hybrid motifFamilyHomologous superfamily
IPR011761 ATP-grasp foldDomainDomain
IPR011764 Biotin carboxylation domainDomainDomain
IPR013815 ATP-grasp fold, subdomain 1FamilyHomologous superfamily
IPR016185 Pre-ATP-grasp domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00121 BiotinDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink