Entity Details

Primary name PSMD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99460
EntryNamePSMD1_HUMAN
FullName26S proteasome non-ATPase regulatory subunit 1
TaxID9606
Evidenceevidence at protein level
Length953
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesPSMD1

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000209 protein polyubiquitination
GO:0000502 proteasome complex
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005838 proteasome regulatory particle
GO:0006521 regulation of cellular amino acid metabolic process
GO:0008540 proteasome regulatory particle, base subcomplex
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle
GO:0016020 membrane
GO:0016579 protein deubiquitination
GO:0022624 proteasome accessory complex
GO:0030234 enzyme regulator activity
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031625 ubiquitin protein ligase binding
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0034515 proteasome storage granule
GO:0035578 azurophil granule lumen
GO:0036388 pre-replicative complex assembly
GO:0038061 NIK/NF-kappaB signaling
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042176 regulation of protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043312 neutrophil degranulation
GO:0043488 regulation of mRNA stability
GO:0043687 post-translational protein modification
GO:0050852 T cell receptor signaling pathway
GO:0055085 transmembrane transport
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070498 interleukin-1-mediated signaling pathway
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1901990 regulation of mitotic cell cycle phase transition
GO:1902036 regulation of hematopoietic stem cell differentiation

Subcellular Location

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Domains

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DomainNameCategoryType
IPR002015 Proteasome/cyclosome repeatRepeatRepeat
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR016642 26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunitFamilyFamily
IPR035266 26S Proteasome non-ATPase regulatory subunit 1FamilyFamily
IPR040623 26S proteasome regulatory subunit RPN2, C-terminalDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PSMD1_HUMANADRM1_MOUSEBioGRID, DIP18497817 18497827 25666615 details