Entity Details

Primary name RING2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99496
EntryNameRING2_HUMAN
FullNameE3 ubiquitin-protein ligase RING2
TaxID9606
Evidenceevidence at protein level
Length336
SequenceStatuscomplete
DateCreated2005-04-26
DateModified2021-06-02

Ontological Relatives

GenesRNF2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000151 ubiquitin ligase complex
GO:0000278 mitotic cell cycle
GO:0000791 euchromatin
GO:0001702 gastrulation with mouth forming second
GO:0001739 sex chromatin
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0007281 germ cell development
GO:0008270 zinc ion binding
GO:0009948 anterior/posterior axis specification
GO:0010467 gene expression
GO:0016604 nuclear body
GO:0031519 PcG protein complex
GO:0035102 PRC1 complex
GO:0035518 histone H2A monoubiquitination
GO:0036353 histone H2A-K119 monoubiquitination
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0061630 ubiquitin protein ligase activity
GO:0070317 negative regulation of G0 to G1 transition
GO:0071339 MLL1 complex
GO:0071535 RING-like zinc finger domain binding

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR032443 RAWUL domainDomainDomain
IPR037937 E3 ubiquitin-protein ligase RING2FamilyFamily
IPR043540 E3 ubiquitin-protein ligase RING1/RING2FamilyFamily

Diseases

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