Entity Details

Primary name CDC6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99741
EntryNameCDC6_HUMAN
FullNameCell division control protein 6 homolog
TaxID9606
Evidenceevidence at protein level
Length560
SequenceStatuscomplete
DateCreated2004-07-19
DateModified2021-06-02

Ontological Relatives

GenesCDC6

GO terms

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GOName
GO:0000076 DNA replication checkpoint signaling
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000166 nucleotide binding
GO:0000278 mitotic cell cycle
GO:0000922 spindle pole
GO:0003688 DNA replication origin binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006260 DNA replication
GO:0006270 DNA replication initiation
GO:0007089 traversing start control point of mitotic cell cycle
GO:0008156 negative regulation of DNA replication
GO:0008285 negative regulation of cell population proliferation
GO:0019900 kinase binding
GO:0030071 regulation of mitotic metaphase/anaphase transition
GO:0032467 positive regulation of cytokinesis
GO:0033314 mitotic DNA replication checkpoint signaling
GO:0036388 pre-replicative complex assembly
GO:0045171 intercellular bridge
GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0048146 positive regulation of fibroblast proliferation
GO:0051233 spindle midzone
GO:0051301 cell division
GO:0051984 positive regulation of chromosome segregation
GO:0072686 mitotic spindle
GO:1904117 cellular response to vasopressin
GO:1904385 cellular response to angiotensin

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR003593 AAA+ ATPase domainDomainDomain
IPR015163 Cdc6, C-terminalDomainDomain
IPR016314 Cell division protein Cdc6/18FamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR041083 AAA lid domainDomainDomain

Diseases

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Interactions

0 interactions

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