Entity Details

Primary name STAT4_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP42228
EntryNameSTAT4_MOUSE
FullNameSignal transducer and activator of transcription 4
TaxID10090
Evidenceevidence at protein level
Length749
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesStat4

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006468 protein phosphorylation
GO:0006952 defense response
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0008283 cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0019221 cytokine-mediated signaling pathway
GO:0042127 regulation of cell population proliferation
GO:0042802 identical protein binding
GO:0043434 response to peptide hormone
GO:0043565 sequence-specific DNA binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0061484 hematopoietic stem cell homeostasis
GO:0071310 cellular response to organic substance

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000980 SH2 domainDomainDomain
IPR001217 Transcription factor STATFamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR012345 STAT transcription factor, DNA-binding, N-terminalFamilyHomologous superfamily
IPR013799 STAT transcription factor, protein interactionDomainDomain
IPR013800 STAT transcription factor, all-alpha domainDomainDomain
IPR013801 STAT transcription factor, DNA-bindingDomainDomain
IPR015988 STAT transcription factor, coiled coilFamilyHomologous superfamily
IPR029839 Signal transducer and activator of transcription 4FamilyFamily
IPR035856 STAT4, SH2 domainDomainDomain
IPR036535 STAT transcription factor, N-terminal domain superfamilyFamilyHomologous superfamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
STAT4_MOUSESTAT1_MOUSEInnateDB22306691 details
STAT4_MOUSEZN467_MOUSEBioGRID12426389 details