Entity Details

Primary name ANM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99873
EntryNameANM1_HUMAN
FullNameProtein arginine N-methyltransferase 1
TaxID9606
Evidenceevidence at protein level
Length371
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesPRMT1

GO terms

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GOName
GO:0001701 in utero embryonic development
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006479 protein methylation
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0007166 cell surface receptor signaling pathway
GO:0008168 methyltransferase activity
GO:0008170 N-methyltransferase activity
GO:0008276 protein methyltransferase activity
GO:0008284 positive regulation of cell population proliferation
GO:0008327 methyl-CpG binding
GO:0016274 protein-arginine N-methyltransferase activity
GO:0016571 histone methylation
GO:0018216 peptidyl-arginine methylation
GO:0019899 enzyme binding
GO:0031175 neuron projection development
GO:0034709 methylosome
GO:0035241 protein-arginine omega-N monomethyltransferase activity
GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity
GO:0042054 histone methyltransferase activity
GO:0042802 identical protein binding
GO:0043985 histone H4-R3 methylation
GO:0044020 histone methyltransferase activity (H4-R3 specific)
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045652 regulation of megakaryocyte differentiation
GO:0045653 negative regulation of megakaryocyte differentiation
GO:0046985 positive regulation of hemoglobin biosynthetic process
GO:0048273 mitogen-activated protein kinase p38 binding
GO:0051260 protein homooligomerization
GO:1900745 positive regulation of p38MAPK cascade
GO:1904047 S-adenosyl-L-methionine binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR025799 Protein arginine N-methyltransferaseFamilyFamily
IPR029063 S-adenosyl-L-methionine-dependent methyltransferaseFamilyHomologous superfamily
IPR041698 Methyltransferase domain 25DomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01752 S-adenosyl-L-homocysteineDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ANM1_HUMANKHDR1_MOUSEIntAct19095693 details
ANM1_HUMANFXL16_MOUSEBioGRID24390425 details