Entity Details

Primary name BAG1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99933
EntryNameBAG1_HUMAN
FullNameBAG family molecular chaperone regulator 1
TaxID9606
Evidenceevidence at protein level
Length345
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesBAG1

GO terms

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GOName
GO:0000774 adenyl-nucleotide exchange factor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006915 apoptotic process
GO:0007166 cell surface receptor signaling pathway
GO:0016020 membrane
GO:0031072 heat shock protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0043066 negative regulation of apoptotic process
GO:0050821 protein stabilization
GO:0051085 chaperone cofactor-dependent protein refolding
GO:0051087 chaperone binding
GO:1900034 regulation of cellular response to heat

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000626 Ubiquitin-like domainDomainDomain
IPR003103 BAG domainDomainDomain
IPR017093 Molecular chaperone regulator BAG-1FamilyFamily
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR036533 BAG domain superfamilyFamilyHomologous superfamily
IPR039773 Molecular chaperone regulator BAGFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB07045 (2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diolDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
BAG1_HUMANHACD3_MOUSEIntAct25036637 details
BAG1_HUMANUBP19_MOUSEIntAct25036637 details