Entity Details

Primary name OPRM_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP42866
EntryNameOPRM_MOUSE
FullNameMu-type opioid receptor
TaxID10090
Evidenceevidence at protein level
Length398
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesOprm1

GO terms

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GOName
GO:0004930 G protein-coupled receptor activity
GO:0004985 G protein-coupled opioid receptor activity
GO:0005245 voltage-gated calcium channel activity
GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0019233 sensory perception of pain
GO:0032100 positive regulation of appetite
GO:0038003 G protein-coupled opioid receptor signaling pathway
GO:0045121 membrane raft
GO:0051930 regulation of sensory perception of pain
GO:0080135 regulation of cellular response to stress
GO:0099056 integral component of presynaptic membrane
GO:0005737 cytoplasm
GO:0005887 integral component of plasma membrane
GO:0005925 focal adhesion
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007218 neuropeptide signaling pathway
GO:0007626 locomotory behavior
GO:0016020 membrane
GO:0019904 protein domain specific binding
GO:0031681 G-protein beta-subunit binding
GO:0042277 peptide binding
GO:0043950 positive regulation of cAMP-mediated signaling
GO:0045019 negative regulation of nitric oxide biosynthetic process
GO:0045471 response to ethanol
GO:0048149 behavioral response to ethanol
GO:0051481 negative regulation of cytosolic calcium ion concentration
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0004979 beta-endorphin receptor activity
GO:0005886 plasma membrane
GO:0030424 axon
GO:0031005 filamin binding
GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway
GO:0032590 dendrite membrane
GO:0032839 dendrite cytoplasm
GO:0042923 neuropeptide binding
GO:0043005 neuron projection
GO:0043951 negative regulation of cAMP-mediated signaling
GO:0060079 excitatory postsynaptic potential
GO:0061358 negative regulation of Wnt protein secretion
GO:0097444 spine apparatus
GO:0099055 integral component of postsynaptic membrane
GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0001965 G-protein alpha-subunit binding
GO:0005768 endosome
GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway
GO:0008022 protein C-terminus binding
GO:0030425 dendrite
GO:0038047 morphine receptor activity
GO:0042755 eating behavior
GO:0043204 perikaryon
GO:0045429 positive regulation of nitric oxide biosynthetic process
GO:0050769 positive regulation of neurogenesis
GO:2000310 regulation of NMDA receptor activity

Subcellular Location

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Subcellular Location
Cell projection
Endosome
Perikaryon
Cell membrane

Domains

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DomainNameCategoryType
IPR000105 Mu opioid receptorFamilyFamily
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001418 Opioid receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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