Entity Details

Primary name LST8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BVC4
EntryNameLST8_HUMAN
FullNameTarget of rapamycin complex subunit LST8
TaxID9606
Evidenceevidence at protein level
Length326
SequenceStatuscomplete
DateCreated2008-04-08
DateModified2021-06-02

Ontological Relatives

GenesMLST8

GO terms

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GOName
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016241 regulation of macroautophagy
GO:0031929 TOR signaling
GO:0031931 TORC1 complex
GO:0031932 TORC2 complex
GO:0032008 positive regulation of TOR signaling
GO:0032148 activation of protein kinase B activity
GO:0032956 regulation of actin cytoskeleton organization
GO:0034198 cellular response to amino acid starvation
GO:0038202 TORC1 signaling
GO:0043539 protein serine/threonine kinase activator activity
GO:1900034 regulation of cellular response to heat
GO:1901796 regulation of signal transduction by p53 class mediator

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR011047 Quinoprotein alcohol dehydrogenase-like superfamilyFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR020472 G-protein beta WD-40 repeatRepeatRepeat
IPR037588 Target of rapamycin complex subunit LST8FamilyFamily

Diseases

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Interactions

3 interactions