Entity Details

Primary name ITAV_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP43406
EntryNameITAV_MOUSE
FullNameIntegrin alpha-V
TaxID10090
Evidenceevidence at protein level
Length1044
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesItgav

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001568 blood vessel development
GO:0001570 vasculogenesis
GO:0001968 fibronectin binding
GO:0002020 protease binding
GO:0005102 signaling receptor binding
GO:0005178 integrin binding
GO:0005245 voltage-gated calcium channel activity
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0006954 inflammatory response
GO:0007155 cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007229 integrin-mediated signaling pathway
GO:0008284 positive regulation of cell population proliferation
GO:0008305 integrin complex
GO:0009566 fertilization
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010888 negative regulation of lipid storage
GO:0016020 membrane
GO:0016477 cell migration
GO:0017134 fibroblast growth factor binding
GO:0019960 C-X3-C chemokine binding
GO:0030335 positive regulation of cell migration
GO:0031258 lamellipodium membrane
GO:0031527 filopodium membrane
GO:0031528 microvillus membrane
GO:0031589 cell-substrate adhesion
GO:0031994 insulin-like growth factor I binding
GO:0032369 negative regulation of lipid transport
GO:0032490 detection of molecule of bacterial origin
GO:0032587 ruffle membrane
GO:0033627 cell adhesion mediated by integrin
GO:0033690 positive regulation of osteoblast proliferation
GO:0034113 heterotypic cell-cell adhesion
GO:0034446 substrate adhesion-dependent cell spreading
GO:0034683 integrin alphav-beta3 complex
GO:0034684 integrin alphav-beta5 complex
GO:0034685 integrin alphav-beta6 complex
GO:0034686 integrin alphav-beta8 complex
GO:0035262 gonad morphogenesis
GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex
GO:0035868 alphav-beta3 integrin-HMGB1 complex
GO:0035987 endodermal cell differentiation
GO:0038027 apolipoprotein A-I-mediated signaling pathway
GO:0038132 neuregulin binding
GO:0042110 T cell activation
GO:0043277 apoptotic cell clearance
GO:0043542 endothelial cell migration
GO:0045124 regulation of bone resorption
GO:0045785 positive regulation of cell adhesion
GO:0046718 viral entry into host cell
GO:0046872 metal ion binding
GO:0048041 focal adhesion assembly
GO:0050431 transforming growth factor beta binding
GO:0050748 negative regulation of lipoprotein metabolic process
GO:0050764 regulation of phagocytosis
GO:0050840 extracellular matrix binding
GO:0050919 negative chemotaxis
GO:0051209 release of sequestered calcium ion into cytosol
GO:0060707 trophoblast giant cell differentiation
GO:0070371 ERK1 and ERK2 cascade
GO:0070588 calcium ion transmembrane transport
GO:0071604 transforming growth factor beta production
GO:0071731 response to nitric oxide
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:1901388 regulation of transforming growth factor beta activation
GO:1905598 negative regulation of low-density lipoprotein receptor activity
GO:1990430 extracellular matrix protein binding
GO:2000536 negative regulation of entry of bacterium into host cell
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR000413 Integrin alpha chainFamilyFamily
IPR013517 FG-GAP repeatRepeatRepeat
IPR013519 Integrin alpha beta-propellorRepeatRepeat
IPR013649 Integrin alpha-2DomainDomain
IPR018184 Integrin alpha chain, C-terminal cytoplasmic region, conserved siteSiteConserved site
IPR028994 Integrin alpha, N-terminalFamilyHomologous superfamily
IPR032695 Integrin domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions