Entity Details

Primary name SRBS1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BX66
EntryNameSRBS1_HUMAN
FullNameSorbin and SH3 domain-containing protein 1
TaxID9606
Evidenceevidence at protein level
Length1292
SequenceStatuscomplete
DateCreated2004-08-31
DateModified2021-06-02

Ontological Relatives

GenesSORBS1

GO terms

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GOName
GO:0001725 stress fiber
GO:0003779 actin binding
GO:0005158 insulin receptor binding
GO:0005634 nucleus
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005912 adherens junction
GO:0005915 zonula adherens
GO:0005925 focal adhesion
GO:0006936 muscle contraction
GO:0007160 cell-matrix adhesion
GO:0008092 cytoskeletal protein binding
GO:0008286 insulin receptor signaling pathway
GO:0016363 nuclear matrix
GO:0030055 cell-substrate junction
GO:0030159 signaling receptor complex adaptor activity
GO:0032869 cellular response to insulin stimulus
GO:0043149 stress fiber assembly
GO:0045121 membrane raft
GO:0045725 positive regulation of glycogen biosynthetic process
GO:0046326 positive regulation of glucose import
GO:0046628 positive regulation of insulin receptor signaling pathway
GO:0046889 positive regulation of lipid biosynthetic process
GO:0048041 focal adhesion assembly
GO:1903078 positive regulation of protein localization to plasma membrane

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cytoplasm
Nucleus
Nucleus matrix

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR003127 SoHo domainDomainDomain
IPR035606 c-Cbl associated protein, SH3 domainDomainDomain
IPR035610 c-Cbl associated protein, SH3 domain 1DomainDomain
IPR035611 c-Cbl associated protein, SH3 domain 2DomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SRBS1_HUMANABL1_MOUSEMINT18768933 details